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RE: [escepticos] Re: Cromagnon mula?



-----Original Message-----
De: Miguel Angel Ruz <marf en tid.es>
Para: escepticos en CCDIS.dis.ulpgc.es <escepticos en CCDIS.dis.ulpgc.es>
Fecha: lunes 13 de abril de 1998 14:45
Asunto: [escepticos] Re: Cromagnon mula?



>>  Por otra parte, el único ADN de neandertal que tenemos indica una
>>   diferencia muy grande con todas las poblaciones humanas. No se
parece más
>>   al ADN europeo que a otros.
>>
>
>
>Me interesa mucho. ¿De dónde hemos sacado ADN de neandertal? ¿Puedes
>enviarme una referencia?

Parece que nadie ha encontrado nada... Yo lo único que he localizado
es ésto:

In 1997 science fiction became science fact when ancient DNA,
believed to be between 30,000 and 100,000 years old, was extracted
from a Neanderthal specimen originally discovered in 1856 in the
Feldhofer Cave of the Neander Valley near Düsseldorf, Ger. In a
technically brilliant tour de force, Matthias Krings, working in
Svante P&Shacek;&Shacek;bo's laboratory at the University of Munich,
Ger., succeeded in piecing together a nucleotide sequence for 379 base
pairs of maternally inherited mitochondrial DNA preserved in a 3.5-g
(0.11-oz) section of the specimen's right humerus. What made this
claim so convincing was that the results were meticulously replicated
by Anne Stone, working in Mark Stoneking's laboratory at Pennsylvania
State University. When the Neanderthal DNA sequence was compared with
the corresponding region in modern humans and chimpanzees, the overall
Neanderthal-human difference was approximately three times greater
than the average difference among modern humans but only about half as
large as the human-chimpanzee difference. Because the Neanderthal
sequence was so unlike any modern human sequence, many experts thought
it highly unlikely that Neanderthals contributed to the human
mitochondrial DNA pool. These data strengthened the case for the
separate-species status of the Neanderthals initially advocated by
William King in 1864, whereby the taxonomic designation Homo
Neanderthalensis is preferred to membership in H. sapiens. It should
be noted, however, that no biparental nuclear DNA was recovered from
the Neanderthal humerus, and, thus, at present there is no way to
refute the  hypothesis that some Neanderthal genes still exist in the
human nuclear gene pool or the conjecture that genetic differences
between human and Neanderthal nuclear DNA are not as large as those
exhibited by the faster-evolving mitochondrial DNA molecule.

Es del Year Book de este año de de la enciclopédica británica.

Saludos.

Daneel.